PUBLICATIONS:
COMPLETE LIST OF PUBLICATIONS ON GOOGLE SCHOLAR - CLICK HERE
Research Articles:
A. Klug, T.J. Park, and G.D. Pollak:
Glycine and GABA Influence Binaural Processing in the Inferior Colliculus of the Mustache Bat.
Journal of Neurophysiology 74: 1701-1713, 1995.
T.J. Park, A. Klug, J.P. Oswald, and B. Grothe: A Novel Circuit in the Bat’s Midbrain
Recruits Neurons into Sound Localization Processing.
Naturwissenschaften 85: 176-179, 1998.
J.P. Oswald, A. Klug, and T.J. Park:
Interaural Intensity Difference Processing in Auditory Midbrain Neurons: Effects of a Transient Early Inhibitory Input.
Journal of Neuroscience 19: 1149-1163, 1999.
A. Klug, E.E. Bauer, and G.D. Pollak:
Multiple Components of Ipsilaterally Evoked Inhibition in the Inferior Colliculus.
Journal of Neurophysiology 82: 593-610, 1999.
E.E. Bauer, A. Klug, and G.D. Pollak:
Features of Contralaterally Evoked Inhibition in the Inferior Colliculus.
Hearing Research 141: 80-96, 2000.
A. Klug, A. Khan, R.M. Burger, E.E. Bauer, L.M. Hurley, L. Yang, B. Grothe, M.B. Halvorsen, and T.J. Park:
Latency as a Function of Intensity in Auditory Neurons: Influences of Central Processing.
Hearing Research 148: 107-123, 2000.
A. Klug, E.E. Bauer, J.T. Hanson, L. Hurley, J. Meitzen, and G.D. Pollak:
Response Selectivity for Species-Specific Calls in the Inferior Colliculus of Mexican Free-Tailed Bats is Generated by Inhibition.
Journal of Neurophysiology 88: 1941-1954, 2002.
E.E. Bauer, A. Klug, and G.D. Pollak:
Spectral Determination of Responses to Species-Specific Calls in the Dorsal Nucleus of the Lateral Lemniscus.
Journal of Neurophysiology 88: 1955-1967, 2002.
T.J. Park, A. Klug, M. Holinstat, and B. Grothe:
Interaural Level Difference Processing in the Lateral Superior Olive and the Inferior Colliculus.
Journal of Neurophysiology 92: 289-301, 2004.
A. Klug and L.O. Trussell:
Activation and deactivation of voltage-dependent K+ channels during synaptically-driven action potentials in the MNTB.
Journal of Neurophysiology 96: 1547-1555, 2006.
J.D. Pfeiffer, R.M. Burger, A. Klug, and B. Grothe:
Axonal Tracing and Calyceal Imaging in the Mammalian Medial Nucleus oft the Trapezoid Body.
Journal of Investigative Medicine 54: S143, 2006.
M. Pecka, T.P. Zahn, B. Saunier-Rebori, I. Siveke, F. Felmy, L. Wiegrebe, A.
Klug, G.D. Pollak, and B. Grothe: Inhibiting the Inhibition: A Neuronal Network for Sound Localization in Reverberant Environments.
Journal of Neuroscience 27: 1782-1790, 2007.
J. Hermann, M. Pecka, H. von Gersdorff, B. Grothe, and A. Klug:
Synaptic Transmission at the Calyx of Held Under In Vivo-Like Activity Levels.
Journal of Neurophysiology 98: 807-820, 2007.
See also associated "Editorial Focus" by nobel laureate E. Neher:
Short-Term Plasticity Turns Plastic. Journal of Neurophysiology 98: 577-578, 2007.
See also Journal Cover.
J. Hermann, B. Grothe, and A. Klug:
Modeling Short-Term Synaptic Plasticity at the Calyx of Held Using In Vivo-Like Stimulation Patterns.
Journal of Neurophysiology 101: 20-30, 2009.
See also Journal Cover.
M. Ford, B. Grothe, and A. Klug:
Fenestration of the Calyx of Held Occurs Sequentially Along the Tonotopic Axis, Is Influenced by Afferent Activity, and Facilitates Glutamate Clearance.
Journal of Comparative Neurology 514: 92-106, 2009.
J. Enes, N. Langwieser, J. Ruschel, M.M. Carballosa-Gonzalez, A. Klug, M.H. Traut, B. Ylera, S. Tahirovic, F. Hofmann, V. Stein, S. Moosmang, I.D. Hentall, and F. Bradke:
Electrical Activity Suppresses Axon Growth through Cav1.2 Channels in Adult Primary Sensory Neurons.
Current Biology 20: 1154-1164, 2010.
M.J. Fischl, T.D. Combs, A. Klug, B. Grothe, and R.M. Burger:
Modulation of synaptic Input by GABAB receptors improves coincidence detection for computation of sound location.
Journal of Physiology 590: 3047-3066, 2012.
See also associated "Perspectives" by M.T. Roberts and N.L. Golding: GABAA receptors sharpen tuning of a sound localization circuit.
Journal of Physiology 590: 2951-2952, 2012.
A. Dondzillo, J.L. Thornton, D.J. Tollin, and A. Klug:
Manufacturing and Using Piggy-back Multibarrel Electrodes for In vivo Pharmacological Manipulations of Neural Responses.
Journal of Visualized Experiments (Video Article) 71: e4358, 1-7, 2013.
S.I. Al-Juboori, A. Dondzillo, E.A. Stubblefield. G. Felsen, T.C. Lei, and A. Klug:
Light scattering properties vary across different regions of the adult mouse brain.
PlosONE, Vol. 7:e67626, 2013.
C.H. Chen, S.H. Pun, P.U. Mak, M.I. Vai, A. Klug, and T.C. Lei:
Circuit models and experimental noise measurements of micropipette amplifiers for extracellular neural recordings from live animals.
Biomed Research International, 10.1155/2014/135026, 2014.
F. Mayer, O. Albrecht, A. Dondzillo and A. Klug:
Glycinergic inhibition to the medial nucleus of the trapezoid body shows prominent facilitation and can sustain high levels of ongoing activity.
Journal of Neurophysiology jn.00864.2013, 2014.
O. Albrecht, A. Dondzillo, F. Mayer, J.A. Thompson, and A. Klug:
Inhibitory projections from the ventral nucleus of the trapezoid body to the medial nucleus of the trapezoid body in the mouse.
Frontiers in Neural Circuits, 8:83. doi: 10.3389/fncir.2014.00083, 2014.
A. Dondzillo, T. Lei, and A. Klug:
A recording chamber for small volume slice electrophysiology.
Journal of Neurophysiology, 114, 2053-2064, 2015.
O. Albrecht and A Klug:
Laser-Guided Neuronal Tracing in Brain Explants.
J Vis Exp. 2015 Nov 25; (105): 10.3791/53333, 2015.
A. Dondzillo, J.A. Thompson, and A Klug:
Recurrent Inhibition to the Medial Nucleus of the Trapezoid Body in the Mongolian Gerbil (Meriones Unguiculatus).
PloS one 11 (8), e0160241, 2016.
C.H. Chen, E.A. McCullagh, S.H. Pun, P.U. Mak, M.I. Vai, P.I. Mak, A. Klug, and T.C. Lei:
An Integrated Circuit for Simultaneous Electrophysiology Recording and Optogenetic Neural Manipulation.
IEEE Transactions in Biomedical Engineering, 64: 557-568, 2017.
E.A. McCullagh, E. Salcedo, M.M. Huntsman, and A. Klug:
Tonotopic alterations in inhibitory input to the medial nucleus of the trapezoid body in a mouse model of Fragile X syndrome.
Journal of Comparative Neurology 525: 3543-3562, 2017.
E.A. McCullagh, P. McCullagh, A. Klug, J.K. Leszczynski, and D.L. Fong:
Effects of an Extended Cage-change Interval on Ammonia Levels and Reproduction in Mongolian Gerbils (Meriones unguiculatus).
J. Am. Assoc. Lab Anim. Sci. 56:713-717, 2017.
Z. Mohammadi, J.M. Kincaid, S.H. Pun, A. Klug, C. Liu C, T.C. Lei:
Computationally inexpensive enhanced growing neural gas algorithm for real-time adaptive neural spike clustering.
Journal of Neural Engineering May 9. doi: 10.1088/1741-2552/ab208c, 2019.
Z. Mohammadi, A. Klug, C. Liu, and T.C. Lei:
Data reduction for real-time enhanced growing neural gas spike sorting with multiple recording channels.
2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), 1084-1087, 2019.
P.T. Ly, A. Lucas, C. Liu, A. Klug, and T.C. Lei:
A stereotaxic platform for small animals based on 3D computer vision and robotics.
2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), 851-854, 2019.
B.Z. Li, S.H. Pun, W. Feng, M.I. Vai, A. Klug, and T.C. Lei:
A Spiking Neural Network Model Mimicking the Olfactory Cortex for Handwritten Digit Recognition.
2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), 1167-1170, 2019.
S. Cheng, Y. Fu, Y. Zhang, W. Xian, H. Wang, B. Grothe, X Liu, X. Xu , A. Klug, and E.A. McCullagh:
Enhancement of de novo sequencing, assembly and annotation of the Mongolian gerbil genome with transcriptome sequencing and assembly from several different tissues.
BMC Genomics 20, 1-6, 2019.
P.K. Wang, S.H. Pun, C.H. Chen, E.A. McCullagh, A. Klug, A. Li, M.I. Vai, P.U. Mak, and T.C. Lei:
Low-latency single channel real-time neural spike sorting system based on template matching.
PloS One 14 (11), e0225138, 2019.
E.A. McCullagh, S. Poleg, N.T. Greene, M.M. Huntsman, D.J. Tollin, and A. Klug:
Characterization of auditory and binaural spatial hearing in a Fragile X Syndrome mouse model.
eNeuro 7(1), 0300-19-2019, 2020.
P.T. Ly, A. Lucas, S.H. Pun, A. Dondzillo, C. Liu, A. Klug, and T.C. Lei:
Robotic Stereotaxic System based on 3D skull reconstruction to improve surgical accuracy and speed.
Journal of Neuroscience Methods, 347: 108955, 2021.
L. Wang, S.H. Pun, P.U. Mak, A. Klug, B.J. Zhang, M.I. Vai and T. Lei:
A real-time correlational combination algorithm to improve SNR for multi-channel neural recordings.
Proceedings of the 2021 IEEE Conference on Circuits and Systems (APCCAS), 213-216, 2021.
B.Z. Li, S.H. Pun, M.I. Vai, A. Klug, and T. Lei:
Axonal Conduction Delay Shapes the Precision of the Spatial Hearing in a Spiking Neural Network Model of Auditory Brainstem.
Proceedings of the 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society. IEEE, 4238-4241,2021.
A. Lucas, S. Poleg, A. Klug, and E.A. McCullagh:
Myelination deficits in the auditory brainstem of a mouse model of Fragile X Syndrome, a possible mechanism for auditory phenotypes.
Frontiers in Neuroscience, 1536, 2021.
Articles (preprint):
E.A. McCullagh, S. Poleg, N.T. Greene, M.M. Huntsman, D.J. Tollin, and A. Klug:
Auditory binaural and spatial hearing impairments in a Fragile X Syndrome mouse model.
BioRxiv, 648717, 2019.
S. Cheng, Y. Fu, Y. Zhang, W. Xian, H. Wang, B. Grothe, X. Lu, X. Xu, A. Klug, and E.A. McCullagh:
De novo assembly of the Mongolian gerbil genome and transcriptome.
BioRxiv, 522516, 2019.
P.T. Ly, A. Lucas, S.H. Pun, A. Dondzillo, C. Liu, A. Klug, and T.C. Lei:
Robotic Stereotaxic System based on 3D skull reconstruction to improve surgical accuracy.
BioRxiv, 894972, 2020.
A. Lucas, S. Poleg, A. Klug, and E.A. McCullagh:
Myelination deficits in the auditory brainstem of a mouse model of Fragile X Syndrome, a possible mechanism for auditory phenotypes.
BioRxiv, 459530, 2021.
B.Z. Li, S.H. Pun, M.I. Vai, T.C. Lei, and A. Klug:
Predicting the Influence of Axon Myelination on Sound Localization Precision Using a Spiking Neural Network Model of Auditory Brainstem.
BioRxiv, 464581, 2021.
Review Articles:
G.D. Pollak, R.M. Burger, T.J. Park, A. Klug, and E.E. Bauer:
Roles of inhibition for transforming binaural properties in the brainstem auditory system.
Hearing Research 168: 60-78, 2002.
G.D. Pollak, R.M. Burger, and A. Klug:
Dissecting the circuitry of the auditory system.
Trends in Neurosciences 26: 33-39, 2003.
G.D. Pollak, A. Klug, and E.E. Bauer:
Processing and Representation of Species-Specific Communication Calls in the Auditory System of Bats.
International Review of Neurobiology 56: 83-121, 2003.
A. Klug:
Short-term plasticity in the auditory brain stem by using in-vivo-like stimulation parameters.
Hearing Research 279: 51-59, 2011.
A. Klug, J.G.G. Borst, B.A. Carlson, C. Kopp-Scheinpflug, V.A. Klyachko, and M.A. Xu-Friedman:
How Do Short-Term Changes at Synapses Fine-Tune Information Processing?
Journal of Neuroscience 32: 14058-14063, 2012.
E.A. McCullagh, S.E. Rotschafer, B.D. Auerbach, A. Klug, L.K. Kaczmarek, K.S. Cramer, R.J. Kulesza, K.A. Razak, J.W. Lovelace, Y. Lu, U. Koch, and Y. Wang:
Mechanisms underlying auditory processing deficits in Fragile X syndrome.
FASEB J. 34: 3501-3518, 2020.
Book Chapters:
A. Klug, E. E. Bauer, J. T. Hanson, and G. D. Pollak:
Processing of species specific vocalizations in the auditory brainstem and midbrain of Mexican free tailed bats (Tadarida brasiliensis).
In: J.S. Kanwal and G. Ehret, (eds.): Behavior and Neurodynamics for Auditory Communication, pp 132-155.
Cambridge University Press, Cambridge, England, 2006.
A. Klug and B. Grothe:
Ethological Stimuli.
In: Palmer and Rees: The Oxford Handbook of Auditory Science: The Auditory Brain, pp 173-192.
Oxford University Press, England, 2010.
The handbook received the George Davey Howells Prize 2010 from London University
and the Royal Society of Medicine for "Most distinguished published contribution to
the advancement of Otolaryngology".